Name one example of a Schedule II controlled substance.

Schedule II controlled substances are characterized by their high potential for abuse, which may lead to severe psychological or physical dependence. They have accepted medical uses in the United States but come with strict regulations.

Among the substances listed, cocaine and oxycodone are both classified as Schedule II. Cocaine is used medically as a local anesthetic in certain procedures, particularly in ENT practices, while oxycodone is a powerful opioid prescribed for severe pain management. Their classification under Schedule II reflects the balance between their potential therapeutic benefits and risks for abuse.

Heroin, which is listed in another choice, is classified as a Schedule I substance, indicating it has no accepted medical use and a high potential for abuse. Marijuana is also classified as Schedule I federally, despite some states legalizing its use for medical or recreational purposes. LSD, like heroin and marijuana, is classified as a Schedule I drug due to its high potential for abuse and lack of accepted medical use.

Thus, cocaine and oxycodone are the correct examples of Schedule II controlled substances due to their recognized medical applications and stringent regulations surrounding their distribution and use.